Conclusion Ovariectomized depression model could successfully be induced by ovariectomy,isolation-housing in combination with 21 days of CUMS. The decrease of 5-HT in hippocampus might be due to the reducing of expression of TPH2 in median raphe nuclei,which leads to lower the synthesis of 5-HT.
结论在卵巢切除术的基础上,联合孤养和21 d CUMS可造成去卵巢抑郁症大鼠模型;模型大鼠海马5-HT含量下降,可能是中缝核TPH2的表达减少所致。
参考来源 - 色氨酸羟化酶2在去卵巢抑郁症模型大鼠中缝核中表达减少·2,447,543篇论文数据,部分数据来源于NoteExpress
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The cytoarchitecture of the raphe nuclei of the brain stem in the tree shrew was studied with Nissl's method.
用尼氏染色法,对树鼩脑干中缝核的细胞构筑进行了研究。
In the mesencephalon, OXB-IR fibers were located in the central gray substance, superior and inferior colliculi, interpeduncular nucleus and raphe nuclei.
在中脑分布于中脑中央灰质、前丘、后丘、脚间核和中缝核;
It is also suggested that this control of pharyngeal movement from the 5 HT neurons in the raphe nuclei is mediated by two subtypes of 5 HT receptor, 5ht3 and 5ht1a.
并推测脑干中缝核群中的5 - HT能神经元对咽肌运动的调控可能经由5ht3和5ht1a两种受体介导。
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